[161] Even in mature women who undergo ovariotomy, as Kepler
found, the pigmentation of the nipples and areola disappears, as well as
of the perineum and anus, the skin taking on a remarkable whiteness.
Normally the sexual centers, and in a high degree the genital orifice,
represent the maximum of pigmentation, and under some circumstances this
is clearly visible even in infancy. Thus babies of mixed black and white
blood may show no traces of negro ancestry at birth, but there will always
be increased pigmentation about the external genitalia.[162] The linea
fusca, which reaches from the pubes to the navel and occasionally to the
ensiform cartilage, is a line of sexual pigmentation sometimes regarded as
characteristic of pregnancy, but as Andersen, of Copenhagen, has found by
the examination of several hundred children of both sexes, it exists in a
slight form in about 75 per cent. of young girls, and in almost as large a
proportion of boys. But there is no doubt that it tends to increase with
age as well as to become marked at pregnancy. At puberty there is a
general tendency to changes in pigmentation; thus Godin found that in 28
per cent, adolescent changes occurred in the eyes and hair at this period,
the hair becoming darker, though the eyes sometimes become lighter.
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